Monday, August 4, 2014

How Phosphatidyl Serine Can Help Imrove Cognition

How Phosphatidyl Serine Can Help Imrove Cognition
Phosphatidyl serine is a phospholipid that is vital to brain cell structure and
function. Phospholipids, found in every cell membrane in our bodies, are molecules with an
amino acid component and a fatty acid component. Phosphatidyl serine plays an important
role in our neurotransmitter systems, metabolism levels of the brain, and maintaining
nerve connections in the brain. It appears that phosphatidyl serine levels naturally
decline with age.



Phosphatidyl serine is a natural extract of lecithin, P. Serine has been the subject
many human clinical trials of memory loss, mood, cognitive performance and learning
ability. Many of the studies show that P. Serine can be helpful for those with age-related
memory impairment. It can even help to optimize cognition in those with no cognitive
impairment!



Aging is associated with altered neuronal membrane lipid composition, enzymatic
activity, decreased neurotransmitter synthesis and metabolism and decreased synaptic
activity. P. Serine appears to reverse some of these changes and also helps re-establish
the normal down-regulation of cortisol secretion that is increased in chronically stressed
individuals. It's benefit in dementia and depression may relate to improved brain cell
membrane fluidity. Phosphatidylserine (100 mg three times daily) has also been shown to
improve the mood and mental function in patients with Parkinson's disease, but exerts no
beneficial effects on muscle control.



See also: Supplements/PhosphatidylCholine.html">Phosphatidyl choline



- Natural Medicine Q & A. Pharmacy Times
- Cenacchi T, et al., Cognitive decline in the elderly: A double-blind, placebo-controlled
multicenter study on efficacy of phosphatidylserine administration. Aging 5, 123-133, 1993
- Funfgeld EW, Baggen M, Nedwidek P, Richstein B, Mistlberger G. Double-blind study with
phosphatidylserine (PS) in parkinsonian patients with senile dementia of Alzheimer's type
(SDAT). Prog Clin Biol Res 317:1235-46, 1989.






No comments:

Post a Comment