Showing posts with label Causes of Lymphocytic Colitis. Show all posts
Showing posts with label Causes of Lymphocytic Colitis. Show all posts

Sunday, October 13, 2013

Lymphocytic Colitis – Symptoms, Causes, Treatment, Diet

Lymphocytic Colitis – Symptoms, Causes, Treatment, Diet

What is Lymphocytic Colitis?


Lymphocytic colitis is the inflammation of the colon that causes persistent non-bloody diarrhea. This is considered a rare condition that seems to provide us a normal colonoscopy result, but shall only reveal its presentation with a mucosal biopsy. Lymphocytic colitis is interconnected with collagenous colitis, a condition that has the same features as with lymphocytic colitis. Both are subtypes of the microscopic colitis, as these conditions are identified or diagnosed by taking a tissue sample for a microscope analysis. The condition is said not to be decisively known, for again its rarity. It has been noted that about 10% of those who suffer chronic diarrhea are believed to be suffering from this lymphocytic colitis. According to epidemiological report, lymphocytic colitis commonly affects those people aging from 60 to 80 years. But rare cases place the young, such as the children, to be affected with this condition. As reported, women are more affected than men.








The condition can be diagnosed through these tests:



  • Stool examination – The exam is only aimed to rule out infection, which may be a possible cause of diarrhea.

  • Colonoscopy or sigmoidoscopy – This shall view the insides of the colon of the client. Usually, the colon of those affected with microscopic colitis is normal. During these procedures, a sample may be extracted and shall be sent to the lab in order to indentify the causative agent or probable cause.


  • Lymphocytic Colitis Symptoms


    As already mentioned, this disease process involves inflammation of the colon thus resulting to bowel irritation. This can be discomforting for the part of the affected and can be energy-wasting at the same time. Presently, here are the manifestations of lymphocytic colitis include the following:



    • Non-bloody, chronic, watery diarrhea that can possibly cause for dehydration

    • Abdominal cramps and bloating

    • Sudden weight loss

    • Nausea and vomiting

    • Fecal incontinence


    Causes of Lymphocytic Colitis


    Lymphocytic colitis is caused by the mere inflammation of the colon, but the etiology of the condition is yet being understood. Primarily, it is caused by the increased levels of the lymphocytes or white blood cell in the colon. Others believed, according to theories, that a bacterial agent has triggered the disease process – for toxins can irritate the lining of a person’s colon. A viral agent is also identified as precipitating factor for lymphocytic colitis those who are immunocompromised are somehow greatly affected for their defenses are weaker and that place them susceptible to infections or inflammations.


    Those at risk for this condition are the people who take medications such as the Clozaril, Comtan, Nexium and Prevacid. NSAIDs also place a person at risk for microscopic colitis. The elderly are also noted to be at risk for developing lymphocytic colitis.


    Lymphocytic Colitis Treatment


    The aim for the treatment course of lymphocytic colitis is to relieve the discomfort of the affected. Here are some of the medical remedies for the condition:


    Surgical removal of the colon


    Partial removal of the affected colon may be necessary in severe cases. This will only be recommended by the doctor when he or she assesses that the condition has gone to its worst.


    Anti-diarrheal drugs


    This shall control diarrhea and avoid dehydration. Loperamide (the first line drug) is usually prescribed along with bismuth subsalicylate (second line) and Lomotil.


    Antispasmodics


    This can relive the abdominal cramping complained by the client. Hyoscyamine is an agent usually prescribed by doctors.


    Cholestyramine


    Cholestyramine is a generic drug that would assist in the treatment process of lymphocytic colitis by absorbing some bile acids that can cause for further diarrhea.


    Corticosteroids
    These can help in reducing the inflammation and help control the discomfort of the affected. Prednisone and budesonide are prescribed by the doctor more frequently.



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    Topical anti-inflammatory drugs


    This can reduce the inflammation process. The topical form is much more recommended than the oral form, because of its possibility to result for gastric upset.


    Immunosuppressants


    These can reduce the activity of inflammation and relax the colon inflammation. These drugs would include methotrexate and azathioprine.


    Lymphocytic Colitis Diet


    The patients’ recommended diet should be complied properly in order to attain a good result. Once he or she is diagnosed with colitis, there is a need to follow this strict diet regimen:


    Low fat, low fiber diet


    This is to avoid gastric irritation and stimulate for more diarrheal episodes. It is known that fat and increased fiber diet can stimulate bowel movement.


    Avoid taking NSAIDs


    This is because of its effect to the colon and its contribution to the development of colitis.


    Increase oral fluid intake


    As a person is at risk for dehydration (constant or chronic diarrhea’s complication), he or she should replace the fluid losses. Providing the client with ORS every after a loose-bowel episode is in action.


    Eat easy-to-digest foods


    These foods are recommended as we need to avoid the stimulation of the gastric system. What happens with hard-to-digest foods is that there shall be more effort exerted by the gastric system, making it a difficult situation and causing another problem. As low-fiber diet is not recommended at first, we need to wean the client slowly so that no abrupt change can harm the colon.


    Avoid irritating foods and avoid lactose-rich diet


    These foods include the spicy, fatty and fried foods. These can only stimulate irritation and for more diarrheal episodes. Milk can place a patient to more episodes of diarrhea most especially if he or she is lactose-intolerant.