What Is Lupus Disease
Lupus is an auto immune disease which affects different organs of the body, joints, skins and internal organs also. This disease is found in both males and female but according to the stats lupus disease is mostly found in females. This is a hereditary disease and it is carried from parents, in special cases lupus disease has nothing to so with family. The normal age group for this disease is from eight to fifty years. Lupus disease is mostly found in Asian and African American peoples.
The main disorder of this disease is that the antibodies starts attacking and destroying the healthy body cells. Most of the lupus disease patients are having this disease because of their family history, but some cases have no family involved in the disease. Certain drugs are also responsible for the lupus disease. Other symptoms are also being related to the lupus disease but only in theory there is still no practical evidence for that.
Symptoms of this disease are very acute, and lupus disease causes extreme pain in joints and other parts of the body. Lupus is well known for causing arthritis in the hands. Patients suffer from rashes on the skin and they also form bruises and painful nodules. Major kidney problems occurs which can even lead to dialysis. In the nervous system part it can cause psychosis, dysfunction and mild headaches. Pulmonary embolism can have blood clots. Chest pain can occur because of heart problem. Heart problem can even create endocarditis and myocarditis. Lupus disease causes several problems in heart and nervous system. Lupus disease causes serious damage to the body regarding internal organs and other body parts. As lupus destroys the healthy cells it is very difficult to predict a perfect area where lupus disease occurs as it can attack any working cell.
There is no permanent cure of the disease and so only the symptoms of the lupus disease can be cured. For different symptoms there are different symptomatic cures, for example pain in joints can be treated by external lotions and anti inflammatory drugs, problems in nervous system can be treated accordingly. The perfect cure of the disease is not at all possible so symptoms are minutely observed and then on that basis medicines are given to the patient. The patients of lupus disease are instructed to live a healthy life style with balanced diet and some daily exercise, exercise helps the body to fight against this disease.
Showing posts with label Rash Lupus. Show all posts
Showing posts with label Rash Lupus. Show all posts
Sunday, June 29, 2014
Tuesday, June 24, 2014
Lupus-the Disease
Lupus-the Disease
Lupus the disease is medically termed as SLE, which is the acronym of Systemic Lupus erythematosus. Systemic Lupus eythematosus is a multi system connective tissue disease, characterized by the presence of widespread tissue damage. This damage is caused by the huge number of anti bodies and also due to the circulating immune complexes.
The significance of this disease is in its cultural prevalence. The systemic lupus erythematosus is found all over the world, but it is more common and more frequent in the United States of America and the Far East. American blacks are more affected with prevalence ratio as high as 1in 250 among females.
The onset is more common in the second and the third decades of life and the female to male ratio is 9: 1
Causes:
Though the exact cause remains to be found out, general studies reveal a genetic background for the disease. Systemic lupus erythematosus is one of the manifestations of the Auto immune diseases, where there is altered immune response of the body immunity against its own cells.
The genetic link is explained by the prevalence of the disease in monozygotic twins and also in related family members
A defect in the Ts- the suppressor lymphocytes of the immune system seems to be a feature of this disease.
Environmental factors
Exposure to Sunlight can provocate an acute flare up in genetically predisposed individuals.
Certain drugs can also cause SLE.
Hormonal factors:
The disease is more prevalent in women of the fertile age, during pregnancy, during puerperium, in women using hormonal contraceptives, in men with a hormonal and chromosomal aberration, called as Klinefelter syndrome. All these factors point to a strong hormonal link in the causation.
Viral infection:
Viral infection has been proved to induce systemic lupus erythematosus in animals, but not yet been proved in humans.
Types of Systemic Lupus Erythematosus:
* Chronic Discoid lupus Erythematosus
* Drug induced Lupus
* Mixed connective tissue disease
* Progressive Systemic Sclerosis
Clinical features:
* Arthritis, arthalgia and fever are the most common trio of presenting symptoms.
* Skin lesions and painful oral or naso pharyngeal ulcers may also be found but are less common.
* Cardio pulmonary features like pericarditis, myocarditis, endocarditis, pleurisy, fibrosing alveolitis and acute shrinking lung syndrome may also be found.
* Renal disease like neprotic syndrome and renal failure are all the worse kind of effects with a very poor prognosis.
* CNS disturbances like Epilepsy, severe depression, dementia, hemiplegia, chore, neuropathy etc.
Lupus the disease is medically termed as SLE, which is the acronym of Systemic Lupus erythematosus. Systemic Lupus eythematosus is a multi system connective tissue disease, characterized by the presence of widespread tissue damage. This damage is caused by the huge number of anti bodies and also due to the circulating immune complexes.
The significance of this disease is in its cultural prevalence. The systemic lupus erythematosus is found all over the world, but it is more common and more frequent in the United States of America and the Far East. American blacks are more affected with prevalence ratio as high as 1in 250 among females.
The onset is more common in the second and the third decades of life and the female to male ratio is 9: 1
Causes:
Though the exact cause remains to be found out, general studies reveal a genetic background for the disease. Systemic lupus erythematosus is one of the manifestations of the Auto immune diseases, where there is altered immune response of the body immunity against its own cells.
The genetic link is explained by the prevalence of the disease in monozygotic twins and also in related family members
A defect in the Ts- the suppressor lymphocytes of the immune system seems to be a feature of this disease.
Environmental factors
Exposure to Sunlight can provocate an acute flare up in genetically predisposed individuals.
Certain drugs can also cause SLE.
Hormonal factors:
The disease is more prevalent in women of the fertile age, during pregnancy, during puerperium, in women using hormonal contraceptives, in men with a hormonal and chromosomal aberration, called as Klinefelter syndrome. All these factors point to a strong hormonal link in the causation.
Viral infection:
Viral infection has been proved to induce systemic lupus erythematosus in animals, but not yet been proved in humans.
Types of Systemic Lupus Erythematosus:
* Chronic Discoid lupus Erythematosus
* Drug induced Lupus
* Mixed connective tissue disease
* Progressive Systemic Sclerosis
Clinical features:
* Arthritis, arthalgia and fever are the most common trio of presenting symptoms.
* Skin lesions and painful oral or naso pharyngeal ulcers may also be found but are less common.
* Cardio pulmonary features like pericarditis, myocarditis, endocarditis, pleurisy, fibrosing alveolitis and acute shrinking lung syndrome may also be found.
* Renal disease like neprotic syndrome and renal failure are all the worse kind of effects with a very poor prognosis.
* CNS disturbances like Epilepsy, severe depression, dementia, hemiplegia, chore, neuropathy etc.
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