Showing posts with label alzheimers. Show all posts
Showing posts with label alzheimers. Show all posts

Tuesday, June 24, 2014

B12 Cures

B12 Cures
Vitamin B-12 supplements can help to remedy a variety of health ailments without our resorting to expensive drugs that might present side effects. B-12 is said to be good for heart health, increased energy, and mental functions though none of these claims have been substantially verified.Vitamin B-12 is one of the water soluble vitamins and is particularly needed for blood components and in proper nerve function. B-12 also plays a role in DNA synthesis and fatty acid metabolism.Natural B-12 Sources: Vitamin B-12 is found in milk and dairy products. Many cereals are fortified with B-12, and cold water fish are also a good source of this vitamin.

History Of Alzheimer's Disease

History Of Alzheimer's Disease
Every day, every minute, experts in the health care fraternity and scientists are learning something new about the Alzheimer's disease. The impetus of research is growing, fuelling excitement and moving scientists a step closer to clearly comprehending the causes of Alzheimer's. Majority, if not all, of today's clinical discoveries are the outcome of basic science that has been researched and funded for several decades by the Alzheimer's Association.



Progressive mental deterioration in old age has been described and recognized ever since time immemorial. This is because elderly people suffer from different forms of senility, but it wasn't until the year 1906 when the disease was formally identified as an independent entity with its own characteristic symptoms and pathology. In 1901, Auguste D, a 51-year old woman, was admitted to the state asylum in Frankfurt suffering from language and cognitive deficits, delusions, auditory hallucinations, aggressive behavior, and paranoia.



Alois Alzheimer, who was a doctor at that hospital at the time, tended to the patient and by the time of her death in 1906, he had already moved to Munich medical school in 1903 to partner with Emil Kraepelin - who was one of the leading German psychiatrists at the time. The hospital in Frankfurt sent Alois the brain of the woman for examination upon which he studied the brain cell abnormalities and a year later, published his talk after presenting the woman's case at a psychiatry meeting.



Alzheimer's disease was given the name by Kraepelin, who named it after Alois Alzheimer, a name still used to refer to this common cause of senile dementia today. When Alois presented his original case of Auguste's cognitive and non-cognitive deficits, he reported that when doing post-mortem, he discovered tangles, plagues and arteriosclerotic changes in the deceased.



Ever since its discovery over 100 years ago, there have been many breakthroughs in the research of AD. During the 60s, scientists discovered a connection between cognitive decline and the amount of tangles and plagues in the brain. During the 70s, scientists made notable strides in comprehending the human body, where AD emerged as a significant scope of study.



As time goes by, and as technology advances, research methods too have advance where specific genes related to the early and late onset types of Alzheimer's have been identified. Because the genetic risk factors cannot single-handedly explain the cause of AD, researchers are exploring also the lifestyle and environment of patients to learn the role they are likely to play in the development of AD.






Monday, June 23, 2014

Alzheimer's Disease Study

Alzheimer's Disease Study
The Alzheimer's disease as been studied by many scientists who are driven by the curiosity to know more about various risk factors that make this genetic condition seem like a mystery. The main question that researchers would want an Alzheimer's disease study to answer is "why are most cases reported at later stages in a person's life?"



It is not easy to conduct research on genetic diseases. The researcher has to collect genetic information from various families. In most cases, it is good to collect these samples from families where many members have suffered from the disease. Most researchers concentrate on late onset cases (between 60 and 70 years).



Before an Alzheimer's disease study is carried, the objective of the research should be clearly described. Typically, the first goal should be to identify the gene that is responsible for triggering production of a protein in the brain that triggers a process of degeneration of brain tissue cells.



The evaluation process should involve diagnosis and other factors which might have contributed to the worsening of the condition. In most cases, there is need to compare patients who are at the same stage of the disease. Various disease-related factors should be monitored and any similarities noted should be highlighted in readiness for an in-depth study.



In some cases, some family member might have died. The measures taken in case of this eventuality will depend on the nature of the study. Some researches require that autopsy samples be extracted and tested in order for cell lines to be established accurately. For genetic-analytical reasons, most researchers argue that in those families whereby two late onset patients are alive, three more family members should also become subjects of the research as well.



The duration of a study into the Alzheimer's disease can extend to three years or even more depending on the variables that have to be studied. Today, most researches on the disease are being conducted along ethnic and racial lines with subjects being categorized into African Americans, Hispanics, Japanese Americans, Asian Americans, the Amish and the Caucasian people.



Previous researches have shown that the Caucasian people rarely suffer from this disease. This finding continues to influence the course of future studies as far as demographic and ethnic factors are concerned. It is only qualified researchers who are authorized to carry out a research such as this one. Only they can access samples that have been extracted from subjects, accurately labeled and stored at well-equipped laboratories. One such repository in the US is National Cell Repository for Alzheimer's Disease (NCRAD).






Alzheimer's Disease Statistics

Alzheimer's Disease Statistics
As the baby boomers in North America approach their sixties, the disease that they fear most is Alzheimer's disease. The risk of getting it increases dramatically once people approach their 60th birthday.



The prevalence rate of this disease can best be understood through analyses of statistics that have been prepared and made available to the public by various North American health institutions.



In the year 1966, 21,166 deaths relating to Alzheimer's diseases were reported in USA according to US Government Statistics. According to the same statistics, this disease was ranked in the 14th position as a cause of deaths in the country. It is estimated that the annual cost of lost wages and health care for caregivers amounts to between $80 and $100 billion.



The 1994th edition of American Journal of Public Health reported that US businesses spend about $61 in an effort to deal with problems relating to the Alzheimer's disease. This shows that this disease should not be underrated and it is the high time more funds were directed into research institutions that specialize in this medical specialty.





According to Alzheimer's Association, 2004, the US government had set aside $640 million for research directly related to this disease. Previously, in 1998, the Canadian Medical Association had reported that the government had spent $9,451 for every individual who was diagnosed with a mild case of the Alzheimer's disease.



An in-depth analysis of these Alzheimer's disease statistics will reveal that the disease poses a real threat to the economic future of many nations. Figures provided by Hospital Episode Statistics in the English Department of Health shows that 78% of all the people seeking Alzheimer's consultation required to be hospitalized in England between 2002 and 2003. In the same year, 53% of all cases of this disease required emergency medical attention in England.



Statistics have it all; the problem of Alzheimer's disease is real and the earlier researchers came up with a new approach of treating it, the better. Patients with this disease tend to spend more time in hospital beds than in the case with many other diseases. Moreover, people with the Alzheimer's tend to suffer from other health problems mainly due to old age.



Many researches are being done with a view to determine the average hospital bed days for a whole year in different states. A comparison needs to be made between these figures and average number of annual hospital consultation episodes. The findings of such a research will be very helpful in coming up with management program for the disease.






Alzheimer's Disease Research Center

Alzheimer's Disease Research Center
Alzheimer's disease is a condition that affects the nervous system of an individual, rendering the patient useless in terms of taking care of themselves or even remembering things. While the disease does not directly kill a person, it makes the patient susceptible to different ailments that may result in death. Alzheimer's disease starts with mild forgetfulness, which worsens till some mental faculties linked to intelligence and personality, are permanently destroyed.



While there are different treatments used to treat the Alzheimer's' disease, at the moment there is no permanent cure, but the Alzheimer's disease and research center is working closely with concerned authorities and experts in the health care field to ensure that a permanent cure is found. The treatment that is available at the moment is meant to delay the onset of the condition's symptoms, or help to counterbalance dementia and delusions that may occur in later stages of the disease.



Alzheimer's disease research center also propose that treatments for the disease are equally under study and investigation for possible efficacy. When the baby boomers get to the age at which they are susceptible to Alzheimer's, it becomes a very huge public concern; hence it is not something that the ADRC should wait to study. ADRC anticipates its occurrence and always endeavor to find ways of preventing it. If not, with the thousands and thousands of more people experiencing dementia and cognitive impairment, it can be quite a challenging and enormous health care concern. ADRC therefore studies the continuum of cognitive changes developing when people age, among other things.



Other functions of the Alzheimer's disease research center is to look for ways of predicting the occurrence of the disease, of course bettering the diagnostic techniques, pin-pointing high-risk individuals, and devising analytical tools that will aid in the pursuit for preventative treatments and the much awaited permanent cure. The US has over 30 Alzheimer's disease research centers, spread across the country and which are funded by the National Institute of Aging of the National Institutes of Health.



Note that the different research centers for AD have unique roles they play in fighting the disease, but they all work together when evaluating potential new medications and other treatments of the disease. The main goal of all ADRC's basic and clinical studies is to enhance patient care as well as function, and generally enhance the quality of life not only for the patient but also for the caregiver.






Alzheimer's Disease Research

Alzheimer's Disease Research
Alzheimer's disease is a fatal brain disorder named after the German physician Alois Alzheimer, who first described it in 1906. Dr Alzheimer was presented with a patient who was suffering from memory loss and difficulty speaking; before any diagnosis was made she died. With the permission of the family Dr. Alzheimer performed an autopsy on her brain and found a dramatic shrinkage and widespread fatty deposits in small blood vessels, dead and dying brain cells as well. He then published his finding and the disease was named after him



Since then there are several efforts being made to research the cause and sure behind Alzheimer's disease. Research is the only way to find a cure for Alzheimer's and to helping the millions already affected by this devastating disease, and those who are being affected each year. The disease is known to double each year



There is several Alzheimer's research centers setup all over the world. These clinics and researchers in the Centers have made major contributions to gain knowledge about the basic biology and clinical presentation of Alzheimer's disease. The goal of such research centers are to accelerate the discovery of new treatment and to make the effective treatment of Alzheimer's disease a reality.



These centers do use individuals who suffer from Alzheimer's disease for evaluation purposes. These centers then research the behavior of normal individuals, individuals with slight memory problems and individuals diagnosed with Alzheimer's disease.



The research centers not only use the patients as subjects but they offer a lot of valuable insight into Alzheimer's disease, educate family members of the disease and delay and treat mild cases of memory loss and dementia.



Alzheimer's disease research clinics are focused on establishing the following,



Conduct research into the causes, treatment, and prevention of Alzheimer's disease



Identify the risk factor



Identify the biological process associated with the disease



Identify and determine brain changes before the actual symptoms show



Develop new and effective treatment



Prevention of the disease



Act as a local and national resource by providing research subjects, data, and materials to researchers in Alzheimer's disease and other brain related disease and abnormalities



Provide the state of the art resources to qualified clinicians and researchers, to assist them with the research process



Inform and educate professionals and the community regarding Alzheimer's disease



Provide and encourage families to cope with their loved ones suffering from Alzheimer's disease



Therefore it is important to fund the research that is carried out today in the hope that future generations might be spared of Alzheimer's disease or better yet that the disease can be cured.






Alzheimer's Disease Patients

Alzheimer's Disease Patients
Alzheimer's disease, also referred to as AD, is a disease that affects the brain. The main effect of this disease is impairment of memory. It is also characterized by problems with reasoning, perception and language. According to many scientists, Alzheimer's disease is caused by increased production of beta-amyloid protein which results to deal of nerve cells in the brain.



At the age of 70, many people face a real risk of getting Alzheimer's disease. About 50 per cent of all people who are above the age of 85 suffer from this condition. This is why many people take this disease as a normal process of ageing. It is also surprising that some people are able to live past their 100th birthday without ever suffering from this debilitating disease.



As the population becomes older and older, cases of Alzheimer's disease are becoming more and more common. Ten per cent of all people who are above the age of 65 are suffering from the disease. All this data shows a rather clear correlation between increase in number of cases and age progression. This is why scientists expected that by the year 2050, 14 million Americans would be living with the disease.



Younger Alzheimer's disease patients get this condition because of mutant genes in their DNA. The gene mutation factor increases the risks of one getting the disease by more than 50 per cent. Late onset of Alzheimer's disease cases is also affected by the genetic risks among these patients. The chromosome 19 contains a gene whose structure greatly affects the amount of risks one is exposed to relating to occurrence of the Alzheimer's disease.



High blood pressure and diabetes are some other risk factors for this disease. Elevated blood cholesterol can increase likelihood of the Alzheimer's disease occurring. People who have completed less than eight years of education are also exposed to a higher risk of this disease.



Although these factors can greatly determine the possibility of the Alzheimer's disease occurring, this is not to say that there is any real danger of eventually getting the disease even in old age. Scientists who happen to be proponents of the amyloid hypothesis often reinforce this assertion.



Many patients go through a combative demeanor in the first six months of the disease. The patient can become psychotic and will talk and talk and scream and scream. Fear seems to conquer these patients; they always fear that someone is trying to kill them. Alzheimer's disease patients lose mental stability completely.






Alzheimer's Disease Management.

Alzheimer's Disease Management.
Research indicates that in Alzheimer's disease management, caregivers are often at increased risk of stress and depression, particularly if they do not have adequate support from family, friends and the society in general. It is important for these caregivers to allow themselves enough rest and relaxation.



Given the nature of the condition, Alzheimer's disease management can be no mean task. Many caregivers find it necessary to employ strategies that enable them to deal with patients' difficult behaviors and stressful situations they have to go through. Below are some suggestions on how to best cope with the management of the disease.



The individual with the disease should be kept out of reach of anything that could pose danger to him. Such things may include matches, knives and so on. The surrounding environment should be kept as safe as possible, especially for the patient. In Alzheimer's disease management, it is helpful to ensure that the patient is engaged. The patient can be engaged in simple and routine activities such as setting the table at meal times or cleaning chores.



Granted, communicating with an Alzheimer's disease patient can sometimes be quite a challenge. Understanding him may be difficult, and being understood can also be a challenge. It is therefore advisable to choose short sentences and simple words. At the same time, it is beneficial to use a calm, gentle tone when communicating to the patient. Alternatively, one can just avoid talking to the patient. Other strategies of communication in Alzheimer's disease management may include allowing the patient enough time for responding and giving feedback and not interrupting, calling the person by name to get his attention when talking to him, and minimizing interfering noise that can distract the conversation. If the person is struggling to find a word, effective Alzheimer's disease management would mean gently trying to provide the word.



The other strategy in Alzheimer's disease management is maintaining familiar mealtime routines, being patient at meal times and giving the patient choices of food. The choices should not be too many though. Also, meals should be served in small portions and several times throughout the day. The caregiver should however be careful to avoid overeating.



Similarly, in Alzheimer's disease management, it is important for the caregiver to find activities that the person can do and is interested in. If there is need, the caregiver should offer support to the person.






Alzheimer's Disease Facts

Alzheimer's Disease Facts
As you learn the Alzheimer's disease facts, you might want to know that it might affect a person closer to your own life. Historically, the condition was first discovered in German by a physician known as Alois Alzheimer, a person who was able to easily chronicle a typical strange condition that had some very terrible effects in a human brain back in 1906. What is important in the line of this condition is to understand it in its entirety, so that you can make the right decision towards changing all the things you might have never known you could, mostly when dealing with an individual having Alzheimer's.



The disease is a mental disorder commonly known as dementia. It is a brain condition that does hamper seriously your brain's ability towards processing a normal or rational thought that inhibits your daily activities as a result. With Alzheimer's therefore, you have the part of your brain that deals with language, memory or thoughts affected badly. It is one of the most leading death causes in all America. After you have the disease, you will have problems with your memory, learning inability, ability to function rather routinely as desired and difficult in making any rational decisions.



The disease does rob many people, mostly in their millions every year their personalities, memories as well as the ability to be able to complete a daily activity. For some time in the history of the disease, there was the belief there was nothing much that could be carried out towards preventing this condition, such that it was a diseases that many were awaiting after reaching golden years. Nonetheless, novel research has suggested that you can be able to prevent yourself from cases of Alzheimer's disease.



The distinct sign and hallmark of Alzheimer's is memory loss. It generally means that those individuals who are over 65 years starts being concerned with the disease after they have started to wield cases of forgetfulness. Forgetfulness might be a herald of Alzheimer's but there are other myriad causes. It is the reason you must learn all that you can about Alzheimer's through the clear signs it gives that you can use a basis of seeking Alzheimer therapy. Taking a test of Alzheimer's will be a distinct plus so that you can ensure you are not only going through a usual case of memory loss that is largely associated with aging individuals. The disease can even send a person into fits of screams and make them delirious.






Alzheimer's Disease Articles

Alzheimer's Disease Articles
If a loved one has ever fallen victim to Alzheimer's disease, then you might have read so many articles on Alzheimer's disease management already. Sometimes, reading too many authors and materials can end up being confusing rather that informative. This article will try to summarize the essential points of knowledge that the entire good articles on Alzheimer's disease management try to pass across.



Basically, Alzheimer's disease is a progressive disorder of the brain disorder. Once the disorder takes root, it relentlessly and progressively destroys the patient's ability to learn new things, to make judgments, to communicate and to remember. The ability to carry out the normal tasks diminishes with time until such times as the memory becomes extinct. Currently, there is no medical cure for Alzheimer's disease.



It is good if the Alzheimer's disease is diagnosed early rather that while in late stages of development. Some ten early symptoms of the disorder entirely which act as the basic warning signs include:



a) Memory loss



b) Misplacing items



c) Confusion, fear, suspicion



d) Language problems



e) Difficulty performing familiar tasks



f) Poor judgment



g) Mood or behavior changes



h) Loss of initiative



i) Becoming disoriented



j) Problems with complex mental tasks



An Alzheimer's patient feels like he or she is losing their mind, mostly as a result of the combination of these symptoms. The combination yields general communication problems, strenuous thinking ability, low reasoning, difficulty in comparing and difficulty in learning new skills or even re-learning the old skills. Alzheimer's disease should be differentiated from the memory loss most people experience with old age. For Alzheimer's the memory loss is significantly greater and frequent besides being accompanied by the other symptoms noted above.



The Alzheimer's disease is not contagious. With proper care, a patient's can have a quality life with those that he or she loves most. Even without cure, offering effective care and critical moral support helps prevent the depression, confusion and self-loath that pushes most patients to worse off mental afflictions.



Although it will seem the best thing to do, the relatives, friends and family of the patient should never isolation the Alzheimer's patient. It is necessary that all of you be available to the patient offering compassionate care, relevant attention and disease management treatment. Never let the patient feel cursed, silly, inept or bothersome. It is quality care, company and attention that makes a patient face the great burden of carrying the Alzheimer condition courageously.