Simvastatin 40 mg
Simvastatin 40 mg is a drug that is used for lowering high cholesterol in blood and comes with the brand name Zocor. It belongs to the class of drugs known as statins. Statins are good in lowering cholesterol in blood by acting as an inhibitor for the main enzyme in liver that produces cholesterol. The main type of cholesterol that is reduced by simvastatin 40 mg is LDL, which is good as it is the key type of cholesterol that is bad for health and is said to be the factor behind artery diseases. Also it works well against the production of triglycerides. On the other hand, statins are a good in increasing the HDL cholesterol level in blood which is termed as the good cholesterol essential for the body.
Simvastatin 40 mg is available only on prescription and is made is various potencies, from 5 mg to 80 mg. This drug is basically prescribed to heart patients that have a history of stroke, diabetes, coronary diseases, peripheral vascular disease or some other cerebrovascular disease. It helps in reducing risk of deaths due to heart attacks and other cardio diseases by keeping a check on bad cholesterol. A dosage adjustment is made by the doctor, according the health of the patient's heart and in general is taken once a day. Increased levels of simvastatin 40 mg can result in muscle toxicity from the drug and the levels may increase if some other drugs are being in addition to simvastatin. Some of these drugs that may decrease elimination of simvastatin are erythromycin, indinavir, cyclosporine, itraconazole etc.
Simvastatin is not advisable for usage if the user is pregnant or nursing. This is because of its indirect effect on the developing fetus. Simvastatin reduces the production of cholesterol and on the other hand the fetus needs cholesterol for development. Therefore, it is advised to only those women who are not likely to come with child. Moreover, simvastatin has a tendency to come in mother's milk, therefore it might cause adverse effects on the nursing baby.
Like many other drugs of medicinal value, simvastatin 40 mg also has its own amount of side effects. Common side effects which can be rectified with the help of minor dosage earache and sore throat changes are:
Some reports have come to tell hypersensitivity reactions have also been seen in some patients. Major side effects include severe muscle inflammation and liver damage. Although the damage to liver is rare but still frequent tests of liver are recommended when statins are under use. If abnormal test are becoming frequent then the use of statins is stopped to be replaced by some other cholesterol absorbing medication. If the liver tests are coming out to be normal only then simvastatin 80 mg should be used. Until then the highest potency recommended is the 40 mg one. Inflammation of muscles can lead to serious complications if remain unchecked. The drug can cause breakdown of muscle protein which enters blood and can end up in death due to kidney failure, which is why caution is necessary.
Simvastatin 40 mg is a drug that is used for lowering high cholesterol in blood and comes with the brand name Zocor. It belongs to the class of drugs known as statins. Statins are good in lowering cholesterol in blood by acting as an inhibitor for the main enzyme in liver that produces cholesterol. The main type of cholesterol that is reduced by simvastatin 40 mg is LDL, which is good as it is the key type of cholesterol that is bad for health and is said to be the factor behind artery diseases. Also it works well against the production of triglycerides. On the other hand, statins are a good in increasing the HDL cholesterol level in blood which is termed as the good cholesterol essential for the body.
Simvastatin 40 mg is available only on prescription and is made is various potencies, from 5 mg to 80 mg. This drug is basically prescribed to heart patients that have a history of stroke, diabetes, coronary diseases, peripheral vascular disease or some other cerebrovascular disease. It helps in reducing risk of deaths due to heart attacks and other cardio diseases by keeping a check on bad cholesterol. A dosage adjustment is made by the doctor, according the health of the patient's heart and in general is taken once a day. Increased levels of simvastatin 40 mg can result in muscle toxicity from the drug and the levels may increase if some other drugs are being in addition to simvastatin. Some of these drugs that may decrease elimination of simvastatin are erythromycin, indinavir, cyclosporine, itraconazole etc.
Simvastatin is not advisable for usage if the user is pregnant or nursing. This is because of its indirect effect on the developing fetus. Simvastatin reduces the production of cholesterol and on the other hand the fetus needs cholesterol for development. Therefore, it is advised to only those women who are not likely to come with child. Moreover, simvastatin has a tendency to come in mother's milk, therefore it might cause adverse effects on the nursing baby.
Like many other drugs of medicinal value, simvastatin 40 mg also has its own amount of side effects. Common side effects which can be rectified with the help of minor dosage earache and sore throat changes are:
- Queasiness, diarrhea, vomiting
- Headache, pain in the abdomen, muscular pain
- Abnormal Liver tests
Some reports have come to tell hypersensitivity reactions have also been seen in some patients. Major side effects include severe muscle inflammation and liver damage. Although the damage to liver is rare but still frequent tests of liver are recommended when statins are under use. If abnormal test are becoming frequent then the use of statins is stopped to be replaced by some other cholesterol absorbing medication. If the liver tests are coming out to be normal only then simvastatin 80 mg should be used. Until then the highest potency recommended is the 40 mg one. Inflammation of muscles can lead to serious complications if remain unchecked. The drug can cause breakdown of muscle protein which enters blood and can end up in death due to kidney failure, which is why caution is necessary.
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